午夜探花

Publications may also be found on .

2025 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2014 | 2013 | 2011 | 2010 | 2009 | 2007 | 2006 | 2003

Increasingly efficient chromatin binding of cohesin and CTCF supports chromatin architecture formation during zebrafish embryogenesis
J. Co脽mann, P.I. Kos, V. Varamogianni-Mamatsi, D. Assenheimer, T. Bischof, T. Kuhn, T. Vomhof, A. Papantonis, L. Giorgetti, and J.C.M. Gebhardt
Nature Communications 16, 1833 (2025),

Mechanisms of gene regulation by SRCAP and H2A.Z
A. Tollenaere, E. Ugur*, S. Dalla-Longa*, C. Deluz, D. Assenheimer, J.C.M. Gebhardt, H. Leonhardt, D.M. Suter
bioRxiv (2025), (*equal contribution)

Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding
D. Huynh*, P. Hoffmeister*, T. Friedrich, K. Zhang, M. Bartkuhn, F. Ferrante, B.D. Giaimo, R. Kovall, T. Borggrefe, F. Oswald^#, and J.C.M. Gebhardt^#
Nature Communications 16, 1259 (2025), (*equal contribution, ^#corresponding author)

to the top

Transcriptional reprogramming by mutated IRF4 in lymphoma
N. Schleussner*, P. Cauchy*, V. Franke, M. Giefing, O. Fornes, N. Vankadari, S.A. Assi, M. Costanza, M.A. Weniger, A. Akalin, I. Anagnostopoulos, T. Bukur, M.G. Casarotto, F. Damm, O. Daumke, B. Edginton-White, J.C.M. Gebhardt, M. Grau, S. Grunwald, M.-L. Hansmann, S. Hartmann, L. Huber, E. K盲rgel, S. Lusatis, D. Noerenberg, N. Obier, U. Pannicke, A. Fischer, A. Reisser, A. Rosenwald, K. Schwarz, S. Sundararaj, A. Weilemann, W. Winkler, W. Xu, G. Lenz, K. Rajewsky, W.W. Wasserman, P.N. Cockerill, C. Scheidereit, R. Siebert, R. K眉ppers, R. Grosschedl, M. Janz, C. Bonifer, and S. Mathas
Nature Communications 14, 6947 (2023), (*equal contribution)

A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency
IRF4 International Consortium, O. Fornes, A. Jia, H.S. Kuehn, Q. Min, U. Pannicke, N. Schleussner, R. Thouenon, Z. Yu, M. De Los Angeles Astbury, C.M. Biggs, M. Galicchio, J.A. Garcia-Campos, S. Gismondi, G. Gonzalez Villarreal, K.J. Hildebrand, M. H枚nig, J. Hou, D. Moshous, S. Pittaluga, X. Qian, J. Rozmus, A.S. Schulz, A.T. Staines-Boone, B. Sun, J. Sun, S. Uwe, E. Venegas-Montoya, W. Wang, X. Wang, W. Ying, X. Zhai, Q. Zhou, A. Akalin, I. Andr茅, T.F.E. Barth, B. Baumann, A. Br眉stle, G. Burgio, J.C. Bustamante, J.-L. Casanova, M.G. Casarotto, M. Cavazzana, L. Chentout, I.A. Cockburn, M. Costanza, C. Cui, O. Daumke, K.L. Del Bel, H. Eibel, X. Feng, V. Franke, J.C.M. Gebhardt, A. G枚tz, S. Grunwald, B. Hoareau, T.R. Hughes, E.-M. Jacobsen, M. Janz, A. Jolma, C. Lagresle-Peyrou, N. Lai, Y. Li, S. Lin, H.Y. Lu, S.O. Lugo-Reyes, X. Meng, P. M枚ller, N. Moreno-Corona, J.E. Niemela, G. Novakovsky, J.J. Perez-Caraballo, C. Picard, L. Poggi, M.-E. Puig-Lombardi, K.L. Randall, A. Reisser, Y. Schmitt, S. Seneviratne, M. Sharma, J. Stoddard, S. Sundararaj, H. Sutton, L.Q. Tran, Y. Wang, W.W. Wasserman, Z. Wen, W. Winkler, E. Xiong, A.W.H. Yang, M. Yu, L. Zhang, H. Zhang, Q. Zhao, X. Zhen, A. Enders, S. Kracker, R. Martinez-Barricarte, S. Mathas, S.D. Rosenzweig, K. Schwarz, S.E. Turvey, and J.-Y. Wang
Science Immunology 8, eade7953 (2023),

to the top

Single-molecule tracking of Nodal and Lefty in live zebrafish embryos supports hindered diffusion model
T. Kuhn, A.N. Landge*, D. M枚rsdorf*, J. Co脽mann, J. Gerstenecker, D. 膶apek, P. M眉ller^#, and J.C.M. Gebhardt^#
Nature Communications 13, 6101 (2022), (*equal contribution, ^#corresponding author)

Stress induced TDP-43 mobility loss independent of stress granules
L. Streit, T. Kuhn, T. Vomhof, V. Bopp, A.C. Ludolph, J.H. Weishaupt, J.C.M. Gebhardt, J. Michaelis^#, and K.M. Danzer^#
Nature Communications 13, 5480 (2022), (^#corresponding author)

Quantum Optical Microphone in the Audio Band
R. Nold, C. Babin, J. Schmidt, T. Linkewitz, M.T.P. Zaballos, R. St枚hr, R. Kolesov, V. Vorobyov, D.M. Lukin, R. Boppert, S. Barz, J. Vu膷kovi膰, J.C.M. Gebhardt, F. Kaiser, and J. Wrachtrup
PRX Quantum 3, 020358 (2022),

A guide to changing paradigms of glucocorticoid receptor function鈥攁 model system for genome regulation and physiology
S. Vettorazzi, D. Nalbantoglu, J.C.M. Gebhardt, and J. Tuckermann
The FEBS Journal 289, 5718鈥�5743 (2022),

Single-molecule tracking (SMT) and localization of SRF and MRTF transcription factors during neuronal stimulation and differentiation
O. Kuchler, J. Gerlach, T. Vomhof, J. Hettich, J. Steinmetz, J.C.M. Gebhardt, J. Michaelis^#, and B. Kn枚ll^#
Open Biology 12, 210383 (2022), (^#corresponding author)

Myosin VI regulates the spatial organisation of mammalian transcription initiation
Y. Hari-Gupta, N. Fili, 脕. Dos Santos, A.W. Cook, R.E. Gough, H.C.W. Reed, L. Wang, J. Aaron, T. Venit, E. Wait, A. Grosse-Berkenbusch, J.C.M. Gebhardt, P. Percipalle, T.-L. Chew, M. Martin-Fernandez, and C.P. Toseland
Nature Communications 13, 1346 (2022),

Periodic synchronization of isolated network elements facilitates simulating and inferring gene regulatory networks including stochastic molecular kinetics
J. Hettich and J.C.M. Gebhardt
BMC Bioinformatics 23, 1鈥�30 (2022),

to the top

Transcription Factor RBPJL Is Able to Repress Notch Target Gene Expression but Is Non-Responsive to Notch Activation
L. Pan*, P. Hoffmeister*, A. Turkiewicz, N.N.D. Huynh, A. Gro脽e-Berkenbusch, U. Knippschild, J.C.M. Gebhardt, B. Baumann, T. Borggrefe^#, and F. Oswald^#
Cancers 13, 5027 (2021), (*equal contribution, ^#corresponding author)

A Fibrinogen Alpha Fragment Mitigates Chemotherapy-Induced MLL Rearrangements
J. Eberle, R.S. Wiehe, B. Gole, L.J. Mattis, A. Palmer, L. St盲ndker, W.-G. Forssmann, J. M眉nch, J.C.M. Gebhardt, and L. Wiesm眉ller
Frontiers in Oncology 11, 689063 (2021),

Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene
A.P. Popp, J. Hettich, and J.C.M. Gebhardt
Nucleic Acids Research 49, 6249鈥�6266 (2021),

Single molecule tracking and analysis framework including theory-predicted parameter settings
T. Kuhn*, J. Hettich*, R. Davtyan, and J.C.M. Gebhardt
Scientific Reports 11, 9465 (2021), (*equal contribution)

to the top

Myosin VI moves on nuclear actin filaments and supports long-range chromatin rearrangements
A. Gro脽e-Berkenbusch, J. Hettich, T. Kuhn, N. Fili, A. Cook, Y. Hari-Gupta, A. Palmer, L. Streit, P. Ellis, C. Toseland^#, and J.C.M. Gebhardt^#
bioRxiv (2020), (#corresponding author)

Inferring quantity and qualities of superimposed reaction rates from single molecule survival time distributions
M. Reisser*, J. Hettich*, T. Kuhn, A.P. Popp, A. Gro脽e-Berkenbusch, and J.C.M. Gebhardt
Scientific Reports 10, 1758 (2020), (*equal contribution)

to the top

Mitotic chromosome binding predicts transcription factor properties in interphase
M. Raccaud, E.T. Friman, A.B. Alber, H. Agarwal, C. Deluz, T. Kuhn, J.C.M. Gebhardt, and D.M. Suter
Nature Communications 10, 487 (2019),

Single-molecule imaging of the transcription factor SRF reveals prolonged chromatin-binding kinetics upon cell stimulation
L. Hipp, J. Beer, O. Kuchler, M. Reisser, D. Sinske, J. Michaelis^#, J.C.M. Gebhardt^#, and B. Kn枚ll^#
PNAS 116, 880鈥�889 (2019), (^#corresponding author)

to the top

Single-molecule imaging correlates decreasing nuclear volume with increasing TF-chromatin associations during zebrafish development
M. Reisser, A. Palmer, A.P. Popp, C. Jahn, G. Weidinger, and J.C.M. Gebhardt
Nature Communications 9, 5218 (2018),

Endonuclease G promotes mitochondrial genome cleavage and replication
R.S. Wiehe, B. Gole, L. Chatre, P. Walther, E. Calzia, A. Palmer, J.C.M. Gebhardt, M. Ricchetti, and L. Wiesm眉ller
Oncotarget 9, 89081 (2018),

Transcription factor target site search and gene regulation in a background of unspecific binding sites
J. Hettich and J.C.M. Gebhardt
Journal of Theoretical Biology 454, 91鈥�101 (2018),

to the top

DNA residence time is a regulatory factor of transcription repression
K. Clau脽*, A.P. Popp*, L. Schulze, J. Hettich, M. Reisser, L.E. Torres, N.H. Uhlenhaut, and J.C.M. Gebhardt
Nucleic Acids Research 45, 11121鈥�11130 (2017), (*equal contribution)

Direct Observation of Cell-Cycle-Dependent Interactions between CTCF and Chromatin
H. Agarwal, M. Reisser, C. Wortmann, and J.C.M. Gebhardt
Biophysical Journal 112, 2051鈥�2055 (2017),

to the top

Spatial organization of RNA polymerase II insidea mammalian cell nucleus revealed by reflectedlight-sheet superresolution microscopy
Z.W. Zhao*, R. Roy*, J.C.M. Gebhardt*, D.M. Suter*, A.R. Chapman, and X.S. Xie
PNAS 111, 681鈥�686 (2014), (*equal contribution)

to the top

From mechanical folding trajectories to intrinsic energy landscapes of biopolymers
M. Hinczewski, C.M. Gebhardt, M. Rief, and D. Thirumalai
PNAS 110, 4500鈥�4505 (2013),

Reply to 鈥渃onvergence of chromatin binding estimates in live cells鈥�
Z.W. Zhao, J.C.M. Gebhardt, D.M. Suter, and X.S. Xie
Nature Methods 10, 692 (2013),

Single-molecule imaging of transcription factor binding to DNA in live mammalian cells
J.C.M. Gebhardt*, D.M. Suter*, R. Roy, Z.W. Zhao, A.R. Chapman, S. Basu, T. Maniatis, and X.S. Xie
Nature Methods 10, 421鈥�426 (2013), (*equal contribution)

to the top

The complex folding network of single calmodulin molecules
J. Stigler, F. Ziegler, A. Gieseke, J.C.M. Gebhardt, and M. Rief
Science 334, 512鈥�516 (2011),

to the top

Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner
M. Brunnbauer, F. Mueller-Planitz, S. K枚sem, T.H. Ho, R. Dombi, J.C.M. Gebhardt, M. Rief, and Z. 脰kten
PNAS 107, 10460鈥�10465 (2010),

Full distance-resolved folding energy landscape of one single protein molecule
J.C.M. Gebhardt, T. Bornschl枚gl, and M. Rief
PNAS 107, 2013鈥�2018 (2010),

The lever arm effects a mechanical asymmetry of the myosin-V-actin bond
J.C.M. Gebhardt, Z. 脰kten, and M. Rief
Biophysical Journal 98, 277鈥�281 (2010),

to the top

Designing the folding mechanics of coiled coils
T. Bornschl枚gl, J. Christof M Gebhardt, and M. Rief
ChemPhysChem 10, 2800鈥�2804 (2009),

Force signaling in biology
J.C.M. Gebhardt, and M. Rief
Science 324, 1278鈥�1280 (2009),

to the top

Myosin V stepping mechanism
G. Cappello, P. Pierobon, C. Symonds, L. Busoni, J.C.M. Gebhardt, M. Rief, and J. Prost
PNAS 104, 15328鈥�15333 (2007),

to the top

Myosin-V is a mechanical ratchet
J.C.M. Gebhardt, A.E.M. Clemen, J. Jaud, and M. Rief
PNAS 103, 8680鈥�8685 (2006),

to the top

The smallest possible nanocrystals of semiionic oxides
P. Persson, J.C.M. Gebhardt, and S. Lunell
Journal of Physical Chemistry B 107, 3336鈥�3339 (2003),

to the top