午夜探花

 

D眉rre P., Eikmanns B.J. (2015) C1-carbon sources for chemical and fuel production by microbial gas fermentation. Review. Curr Opin Biotechnol. 35:63-72

Clermont L., Macha A., M眉ller L.M., Derya S.M., von Zaluskowski P., Eck A., Eikmanns B.J., Seibold G.M. (2015) The 伪-glucan phosphorylase MalP of Corynebacterium glutamicum is subject to transcriptional regulation and competitive inhibition by ADP-glucose. J Bacteriol. 197(8):1394-407

Eikmanns B.J. & Blombach B. (2014a) The pyruvate dehydrogenase complex of Corynebacterium glutamicum: an attractive target for metabolic engineering. J. Biotechnol. 192:339-345

Eikmanns B.J. & Blombach B. (2014b) Isobutanol. In: Bioprocessing of renewable resources to commodity bioproducts. V.S. Bisaria & A. Kondo (Eds.), John Wiley and Sons, Inc., pp. 327-352, ISBN: 978-1-118-17583-5

Rado拧 D., Turner D.L., Fonseca L., Carvalho A.L., Blombach B., Eikmanns B., Neves A.R. & Santos H. (2014) The effect of CO2 on anaerobic succinate production by Corynebacterium glutamicum. carbon flux analysis by 13C-NMR. Appl. Environ. Microbiol. 80:3015-3024

Oldiges M., Eikmanns B.J. & Blombach B. (2014) Application of metabolic engineering for the biotechnological production of L-valine. Appl. Microbiol. Biotechnol. 98:5859-5870

Blombach B. & Eikmanns B.J. (2014c) Ma脽geschneiderte Zellfabriken - Corynebacterium glutamicum als Produzent von Pyruvat-abgeleiteten Produkten. BIOspektrum 06.14:696-699

B眉ckle-Vallant V., Krause F., Messerschmidt S. & Eikmanns B.J. (2014) Metabolic engineering of Corynebacterium glutamicum for 2-ketoisocaproate production. Appl. Microbiol. Biotechnol. 98:297-311

Wieschalka S., Blombach B., Bott M. & Eikmanns B.J. (2013) Bio-based production of organic acids with Corynebacterium glutamicum. Microb. Biotechnol. 6:87-102

Lindner S.N., Petrov D.P., Hagmann C.T., Henrich A., Kr盲mer R., Eikmanns B.J., Wendisch V.F. & Seibold G.M. (2013) Phosphotransferase system- (PTS-) mediated glucose uptake is repressed in phosphoglucoisomerase-deficient Corynebacterium glutamicum strains. Appl. Environ. Microbiol. 79:2588-2595

Klaffl S., Brocker M., Kalinowski J., Eikmanns B.J. & Bott M. (2013) Complex regulation of the PEP carboxykinase gene pck and characterization of ist GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum. J. Bacteriol. 195:4283-4296

Seibold G. & Eikmanns B.J. (2013) Inactivation of the phosphoglucomutase gene pgm in Corynebacterium glutamicum affects cell shape development and glycogen metabolism. Biosci. Rep. 33 (4), art:e00059

Buchholz J., Schwentner A., Brunnenkan B., Gabris C., Grimm S., Gerstmeir R., Takors R., Eikmanns B.J. & Blombach B. (2013) Platform engineering: Corynebacterium glutamicum with reduced pyruvate dehydrogenase complex activity for improveed production of L-lysine, L-valine, 2-ketoisovalerate. Appl. Environ. Microbiol. 19:5566-5575

Bott M. & Eikmanns B.J. (2012) TCA cycle and glyoxylate shunt of Corynebacterium glutamicum. In: Corynebacterium glutamicum: Biology and Biotechnology (Microbiology Monographs), Yukawa H. & Inui  M. (eds), Springer Verlag Berlin Heidelberg, pp. 281-314 

Laslo T., von Zaluskowski P., Gabris C., Lodd E., R眉ckert C., Dangel P., Kalinowski J., Auchter M., Seibold G., Eikmanns B. J. (2012) Arabitol metabolism of Corynebacterium glutamicum and its regulation by AtlR. J. Bacteriol. 194:941-55.

Wieschalka S., Blombach B., Eikmanns B. J. (2012) Engineering Corynebacterium glutamicum for the production of pyruvate. Appl. Microbiol. Biotechnol. 94:449-59.

Blombach B. & Eikmanns B.J. (2011) Current knowledge on isobutanol production with Escherichia coli, Bacillus subtilis and Corynebacterium glutamicum. Bioeng. Bugs 2(6):346-50

Seibold G.M., Breitinger K.J., Kempkes R., Both L., Kr盲mer M., Dempf S. & Eikmanns B.J. (2011) The glgB encoded glycogen branching enzyme is essential for glycogen accumulation in Corynebacterium glutamicum. Microbiology 157:3243-51

Bartek T., Blombach B., Lang S., Eikmanns B.J., Oldiges M., N枚h K. & Noack S. (2011) Comparative 13C-metabolic flux analysis of PDHC-deficient L-valine producting Corynebacterium glutamicum. Appl. Environ. Microbiol. 77:6644-6652

Auchter M., Laslo T., Fleischer C., Schiller L., Arndt A., Gaigalat L., Kalinowski J. & Eikmanns B.J. (2011) Control of adhA and sucR expression by the SucR regulator in Corynebacterium glutamicum. J. Biotechnol. 152:77-86

van der Ooyen J., Emer D., Bussmann M., Bott M., Eikmanns B.J. & Eggeling L. (2011) Citrate synthase in Corynebacterium glutamicum is encoded by two gltA transcripts, which are controlled by RamA, RamB and GlxR. J. Biotechnol. 154:140-148

Auchter M., Cramer A., H眉ser A., R眉ckert C., Emer D., Schwarz P., Arndt A., Lange C., Kalinowski J., Wendisch V.F. & Eikmanns B.J. (2011) RamA and RamB are global regulators in Corynebacterium glutamicum and control enzymes of the central metabolism. J. Biotechnol. 154:126-139

Blombach B., Riester T., Wieschalka S., Ziert C., Youn J.-W., Wendisch V.F. & Eikmanns B.J. (2011) Corynebacterium glutamicum tailored for efficient isobutanol production. Appl. Environ. Microbiol. 77:3300-10

Krause F.S., Blombach B., Eikmanns B.J. (2010) Metabolic engineering of Corynebacterium glutamicum for 2-ketoisovalerate production. Appl Environ Microbiol. 76(24):8053-61.

Woo H.M., Noack S.,Seibold G., Willbold S., Eikmanns B.J. & Bott M. (2010) A link between phosphate starvation and glycogen metabolism in Corynebacterium glutamicum revealed by metabolomics. Appl. Environ. Microbiol. 76:6910-6919.

Seibold G.M., Hagmann C., Schietzel M., Emer D., Auchter M., Schreiner J. & Eikmanns B.J. (2010) The transcriptional regulators RamA and RamB are involved in the regulation of glycogen synthesis in Corynebacterium glutamicum. Microbiology 156:1256-1263.

Krause F.S., Henrich A., Blombach B., Kr盲mer R., Eikmanns B. J. & Seibold G. M. (2010) Increased glucose utilization in Corynebacterium glutamicum by use of maltose and its application for the improvement of L-valine productivity. Appl. Environ. Microbiol. 76:370-374.

Bartek T., Blombach B., Z枚nnchen E., Makus P., Lang S., Eikmanns B. J. & Oliges M. (2010) Importance of NADPH supply for improved L-valine formation in Corynebacterium glutamicum. Biotechnol. Prog. 26:361-371.

Bartek T., Rudolf C., Ker脽en U., Klein B., Blombach B., Eikmanns B.J. & Oldiges M. (2010) Studies on substrate utilization in L-valine-producing Corynebacterium glutamicum strains deficient in pyruvate dehydrogenase complex. Bioprocess Biosyst. Eng. 33:873-883.

Klaffl S. & Eikmanns B.J. (2010) Genetical and functional analysis of the soluble oxaloacetate decarboxylase from Corynebacterium glutamicum. J. Bacteriol. 192:2604-2612.

Micklinghoff J., Breitinger K., Schmidt M., Geffers R., Eikmanns B.J. & Bange F.C. (2009) The role of the transcriptional regulator RamB (Rv0465c) in control of the glyoxylate cycle in Mycobacterium tuberculosis. J. Bacteriol. 191:7260-7269.

Bussmann M., Emer D., Hasenbein S., Degraf S., Eikmanns B.J. & Bott M. (2009) Transcriptional control of the succinate dehydrogenase operon sdhCAB of Corynebacterium glutamicum by the cAMP-dependent regulator GlxR and the LuxR-type regulator RamA. J. Biotechnol. 143:173-182.

Blombach B., Arndt A., Auchter M. & Eikmanns B.J. (2009) L-Valine production during growth of pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum in the presence of ethanol or by inactivation of the transcriptional regulator SugR. Appl. Environ. Microbiol. 75:1197-1200.

Seibold G.M., Wurst M. & Eikmanns B.J. (2009) Roles of maltodextrin and glycogen phosphorylases in maltose utilisation and glycogen metabolism in Corynebacterium glutamicum. Microbiology 155:347-358.

Blombach B., Hans S., Bathe B. & Eikmanns B.J. (2009) Acetohydroxyacid synthase: A novel target to improve L-lysine production with Corynebacterium glutamicum. Appl. Environ. Microbiol. 75:419-427.

Emer D., Krug A., Eikmanns B.J. & Bott M. (2009) Complex expression control of the Corynebacterium glutamicum aconitase gene: identification of RamA as a third transcriptional regulator besides AcnR and RipA. J. Biotechnol. 140:92-98.

Jolkver E., Ballan S., Emer D., Kr盲mer R., Eikmanns B.J. & Marin K. (2009) Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum. J. Bacteriol. 191: 940-948.

Veit A., Rittmann D., Georgi T., Youn J.-W., Eikmanns B.J. & Wendisch V.F. (2009) Pathway identification combining metabolic flux and functional genomics analyses: acetate and propionate activation by Corynebacterium glutamicum. J. Biotechnol. 140:75-83.

Auchter M., Arndt A. & Eikmanns B.J. (2009) Dual transcriptional control of acetaldehyde dehydrogenase gene ald of Corynebacterium glutamicum by RamA and RamB. J. Biotechnol. 140:84-91.

Blombach B., Cramer A., Eikmanns B.J. & Schreiner M. (2009) RamB is an activator of the E1p gene in Corynebacterium glutamicum. J. Mol. Microbiol. Biotechnol. 16:236-239.

Arndt A. & Eikmanns B.J. (2008). Regulation of carbon metabolism in Corynebacterium glutamicum. In: Corynebacteria: Genomics and Molecular Biology, Burkovski A. (ed), pp. 155-182, Horizon Scientific press, Norwich, UK

Blombach B., Schreiner M.E., Bartek T., Oldiges M. & Eikmanns B.J. (2008) Corynebacterium glutamicum tailored for high yield L-Valine production. Appl. Microbiol. Biotechnol. 79:471-479.

Arndt A., Auchter M., Ishige T., Wendisch V.F. & Eikmanns B.J. (2007) Ethanol catabolism in Corynebacterium glutamicum. J. Mol. Microbiol. Biotechnol. 15:222-233.

Seibold G.M. & Eikmanns B.J. (2007b) The glgX gene product of Corynebacterium glutamicum is required for glycogen degradation and for fast adaptation to hyperosmotic stress. Microbiology 153:2212-2220.

Seibold G., Dempf S., Schreiner J. & Eikmanns B.J. (2007a) Glycogen formation in Corynebacterium glutamicum and role of ADP-glucose pyrophosphorylase. Microbiology 153:1275-1285.

Blombach B., Schreiner M., Moch M., Oldiges M. & Eikmanns B.J. (2007) Effect of pyruvate dehydrogenase complex-deficiency on L-lysine production with Corynebacterium glutamicum. Appl. Microbiol. Biotechnol. 76:615-623.

Arndt, A. & Eikmanns B.J. (2007) The alcohol dehydrogenase gene adhA in Corynebacterium glutamicum is subject to carbon catabolite repression. J. Bacteriol. 189:7408-7416.

Blombach B., Schreiner M.E., Holatko, J., Bartek T., Oldiges M. & Eikmanns B.J. (2007) L-Valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum. Appl. Environm. Microbiol. 73:2079-2084.

Cramer, A. & Eikmanns, B.J. (2007) RamA, the Transcriptional Regulator of Acetate Metabolism in Corynebacterium glutamicum, Is Subject to Negative Autoregulation. J Mol Microbiol Biotechnol. 12(1-2):51-59.

Cramer, A., Auchter, M., Frunzke, J. & Eikmanns, B.J. (2007) RamB, the transcriptional regulator of acetate metabolism in Corynebacterium glutamicum is subject to regulation by RamA and RamB. J Bacteriol. 189:1145-1149.

Wendisch V.F., Bott M. & Eikmanns B.J. (2006) Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids. Curr. Opin. Microbiol. 9:268-274.

Mansi M., Cozzone A.J., Shiloach J. & Eikmanns B.J. (2006) Control of carbon flux via enzymes of central and intermediary metabolism during growth of Escherichia coli on acetate. Curr. Opin. Microbiol. 9:173-179.

Cramer A., Gerstmeir R., Schaffer S., Bott M. & Eikmanns B.J. (2006) Identification of RamA, a novel LuxR-type transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum. J. Bacteriol. 188:2554-2567.

Seibold G., Auchter M., Berens S., Kalinowski J. & Eikmanns B.J. (2006) Utilization of soluble starch by a recombinant Corynebacterium glutamicum strain: growth and lysine production. J. Biotechnol. 124:381-391.

Schreiner M.E., Riedel C., Holatko J., Patek M. & Eikmanns B.J. (2006) Pyruvate: Quinone Oxidoreductase from Corynebacterium glutamicum: Molecular Analysis of the pqo Gene, Significance of the Enzyme and Phylogenetic Aspects. J. Bacteriol. 188:1341-1350.

Schreiner M.E., Fiur D., Holatko J., Patek M. & Eikmanns B.J. (2005) E1 Enzyme of the Pyruvate Dehydrogenase Complex in Corynebacterium glutamicum: Molecular Analysis of the Gene and Phylogenetic Aspects. J. Bacteriol. 187:6005-6018.

Eikmanns B.J. (2005) Central metabolic pathways of Corynebacterium glutamicum: tricarboxylic cycle and anaplerotic reactions. In Handbook of Corynebacterium glutamicum, Eggeling, L. and Bott, M. (eds), pp. 241-276, CRC Press, Boca Raton, Florida, USA

Sauer U. & Eikmanns B.J. (2005) The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria. FEMS Microbiol. Rev. 29:765-794.

Schreiner M & Eikmanns B.J. (2005) Pyruvate: quinone oxidoreductase from Corynebacterium glutamicum: Purification and biochemical characterization. J. Bacteriol. 187:862-871.

Gerstmeir R., Cramer A., Dangel P., Schaffer S. & Eikmanns B.J. (2004) RamB, a novel transcriptional regulator of genes involved in acetate metabolism of Corynebacterium glutamicum. J. Bacteriol. 186:2798-2809.

Kalinowski J., Bathe B., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kr盲mer R., Linke B., McHardy A.C., Meyer F., M枚ckel B., Pfefferle W., P眉hler A., Rey D., R眉ckert C., Rupp, O., Sahm H., Wendisch V.F., Wiegr盲be I. & Tauch A. (2003) The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins. J. Biotechnol. 104:5-25.

Gerstmeir R., Wendisch V.F., Schnicke S., Ruan H., Farwick M., Reinscheid D. & Eikmanns B.J. (2003) Acetate metabolism and its regulation in Corynebacterium glutamicum. J. Biotechnol. 104:99-122.